Dig into your protocols like never before.

Lab notebooks do not track your benchwork efficiently. This is why we invented a new tool fully dedicated to documenting all your protocol versions and metadata. We called it Make.

Make protocol editor on a laptop

How it works.

  1. Protocol design

    Craft protocols at high speed using our in-house text edition technology. In few shortcuts, all your variables and materials are registered and you are good to go.

    Protocol design in Make

  2. Protocol launch & versioning

    Every iteration of your lab work can be saved in Glyphe, allowing you to return to any stage of your experimental journey on demand.

    Protocol versions

  3. Result analysis

    Centralise and connect all your protocol versions with their related results. In a single space, you can easily navigate your work and tap into advanced analytics to reflect on your performance.

    Result analysis

  4. Adjustment & relaunch

    Develop new strategies to optimize your protocol, design and try as many iterations as needed, until you’re satisfied with the result.

    Protocol log entries

Protocols have never been
that well documented & tracked.

Make offers many features allowing you and your team to share experimental insights and stay up to date with the latest changes on your protocols.

Turn your bench thoughts into Notes.

Instructive note
Note card

Create custom graphs to analyse your protocol performances.

Your protocols are full of relevant data for your research. We format them to make your analysis easier.

Custom graphs in Make

Welcome to a new era.
Tracking 2.0 has started.

Just like in coding, we built a system of instances & branches to help bioresearch teams document their progress and work through iterations. It’s simple and powerful.

Western blot

  • WB-01 · VER · v1 · RIPA · 1:1000 · milk 5% · wet
  • WB-02 · ITE · v1 · run 2
  • WB-03 · ITE · v1 · run 3
  • WB-04 · UPD · v1.1 · 1:2000
  • WB-05 · UPD · v1.2 · 1:5000
  • WB-06 · UPD · v1.3 · 40 µg lysate
  • WB-07 · VER · v2 · NP-40 · 1:1000 · milk 5% · wet
  • WB-08 · ITE · v2 · run 2
  • WB-09 · VER · v3 · RIPA · 1:1000 · BSA 5% · wet
  • WB-10 · UPD · v3.1 · BSA 3%
  • WB-11 · VER · v4 · RIPA · 1:1000 · milk 5% · semi-dry
  • WB-12 · ITE · v4 · run 2
  • WB-13 · VER · v5 · RIPA · 1:1000 · milk 5% · wet · PVDF
  • WB-14 · UPD · v5.1 · 4°C ON
  • WB-15 · ITE · v5.1 · run 2

Immunofluorescence

  • IF-01 · VER · v1 · PFA 4% 10 min · Triton 0.1% · BSA 3% · 1:200 · 1 h RT
  • IF-02 · UPD · v1.1 · PFA 15 min
  • IF-03 · VER · v2 · MeOH -20°C 10 min · none · BSA 3% · 1:200 · 1 h RT
  • IF-04 · ITE · v1.1 · run 2
  • IF-05 · ITE · v2 · run 2
  • IF-06 · UPD · v1.2 · 1:500
  • IF-07 · VER · v3 · PFA 4% 10 min · Saponin 0.1% · BSA 3% · 1:200 · 1 h RT
  • IF-08 · ITE · v1.2 · run 2
  • IF-09 · VER · v4 · PFA 4% 10 min · Triton 0.1% · goat serum 5% · 1:200 · 1 h RT
  • IF-10 · UPD · v3.1 · Triton 0.25%
  • IF-11 · ITE · v4 · run 2
  • IF-12 · UPD · v1.3 · 4°C ON
  • IF-13 · VER · v5 · v1.3 + DAPI 1 µg/mL · ProLong Gold
  • IF-14 · UPD · v5.1 · Hoechst 1 µg/mL
  • IF-15 · ITE · v5.1 · run 2

MTT

  • MT-01 · VER · v1 · 5k/well · 0.5 mg/mL · 4 h · DMSO · doxorubicin 0–10 µM · 48 h
  • MT-02 · UPD · v1.1 · 10k/well
  • MT-03 · UPD · v1.2 · 1 mg/mL
  • MT-04 · UPD · v1.3 · 2 h
  • MT-05 · VER · v2 · 5k/well · 0.5 mg/mL · 4 h · SDS 10% HCl 0.01 M · doxorubicin 0–10 µM · 48 h
  • MT-06 · VER · v3 · 5k/well · 0.5 mg/mL · 4 h · isopropanol HCl 0.04 M · doxorubicin 0–10 µM · 48 h
  • MT-07 · UPD · v3.1 · 24 h exposure
  • MT-08 · VER · v4 · 5k/well · 0.5 mg/mL · 4 h · DMSO · cisplatin 0–50 µM · 48 h
  • MT-09 · VER · v5 · 5k/well · 0.5 mg/mL · 4 h · DMSO · paclitaxel 0–100 nM · 48 h
  • MT-10 · UPD · v5.1 · 72 h exposure
  • MT-11 · ITE · v1 · run 2
  • MT-12 · ITE · v1.3 · run 2
  • MT-13 · ITE · v2 · run 2
  • MT-14 · ITE · v4 · run 2
  • MT-15 · ITE · v5.1 · run 2

RT-qPCR

  • QP-01 · VER · v1 · GAPDH · 300 nM · 60°C · 25 ng · SYBR
  • QP-02 · ITE · v1 · run 2
  • QP-03 · ITE · v1 · run 3
  • QP-04 · ITE · v1 · run 4
  • QP-05 · UPD · v1.1 · 200 nM
  • QP-06 · UPD · v1.2 · 400 nM
  • QP-07 · UPD · v1.3 · 62°C
  • QP-08 · ITE · v1.3 · run 2
  • QP-09 · VER · v2 · ACTB · 300 nM · 60°C · 25 ng · SYBR
  • QP-10 · VER · v3 · HPRT1 · 300 nM · 60°C · 25 ng · SYBR
  • QP-11 · UPD · v3.1 · 50 ng
  • QP-12 · VER · v4 · GAPDH · 300 nM · 60°C · 25 ng · TaqMan
  • QP-13 · VER · v5 · GAPDH+ACTB · 300 nM · 60°C · 25 ng · SYBR
  • QP-14 · UPD · v5.1 · 45 cycles
  • QP-15 · ITE · v5.1 · run 2

CRISPR-Cas9 RNP

  • CR-01 · VER · v1 · sg1 · 1:1 · 2 µg · CM-137 · HEK293T
  • CR-02 · VER · v2 · sg2 · 1:1 · 2 µg · CM-137 · HEK293T
  • CR-03 · ITE · v1 · run 2
  • CR-04 · UPD · v1.1 · 1:2
  • CR-05 · ITE · v2 · run 2
  • CR-06 · UPD · v1.2 · 4 µg
  • CR-07 · ITE · v1.2 · run 2
  • CR-08 · VER · v3 · sg1+sg2 · 1:1 · 2 µg · CM-137 · HEK293T
  • CR-09 · UPD · v3.1 · 1:3
  • CR-10 · VER · v4 · sg1 · 1:1 · 2 µg · CM-137 · HeLa
  • CR-11 · ITE · v3.1 · run 2
  • CR-12 · UPD · v4.1 · DS-150
  • CR-13 · VER · v5 · sg1 · 1:1 · 2 µg · CM-137 · Jurkat
  • CR-14 · UPD · v5.1 · 5e5 cells
  • CR-15 · ITE · v5.1 · run 2

Publish and share validated protocols to your peers.

Meet Karl, a publishing system we are building to help scientists share their knowledge and data at the scale they choose, with full control over their IP. We hope it becomes a complementary approach to sharing your experimental mistakes and successes with your community.

Karl protocol library, with a published protocol open in the side panel

QFA

Do you have more questions?

DiscordContact us